VOA Podcast 17a: Dr Eleanor Raffan - dogs, evolution, adiposity and its influence on osteoarthritis
Russell Chandler talks with Dr Eleanor Raffan about the advantages and disadvantages of a predilection towards obesity in dogs. They discuss the genetic inheritance of this trait and how environment and diet, mediated by epigenetics, influences this risk. The interaction of adiposity and osteoarthritis via the adipokine-mediated inflammatory pathways is also explored.